Children’s Healthcare of Atlanta Study Shows Steroids Reduce Opioid Use Following Posterior Spinal Fusion Surgery for Scoliosis

ATLANTA (Oct. 21, 2020) – Teens undergoing posterior spinal fusion surgery for adolescent idiopathic scoliosis decreased post-operative opioid use by 40% when steroids were added to their pain management treatment, according to findings published today in the Journal of Bone and Joint Surgery led by Nicholas Fletcher, MD, an Orthopedic Surgeon and Medical Director of Spine Quality and Outcomes at Children’s Healthcare of Atlanta. Additionally, patients were twice as likely to walk at their initial inpatient physical therapy session and the average hospital stay decreased to under two days.

“We’ve greatly reduced the postoperative challenges faced by kids and their families,” said Dr. Fletcher, who is also an Associate Professor of Orthopedic Surgery at Emory University School of Medicine. “Patients are getting back to school quicker and their pain is diminished after surgery allowing for them to return to their normal activities sooner.”

Scoliosis is a curve in the spine, which appears like a “C” or “S” from the back and is the most common spinal abnormality in children, affects about 3% of teens ages 10 to 18 in the U.S. The Orthopaedics and Sports Medicine Center at Children’s performs about 500 spinal fusion surgeries each year in severe cases, more than any other children’s hospital in the country, according to the Pediatric Health Information System (PHIS). The condition is often detected during school screenings by the presence of uneven shoulders, a rib hump or a lower back hump. Scoliosis usually develops during the teenage growth spurt and is not the result of bad posture, a heavy backpack, poor diet or playing sports. While the cause is unknown, it may run in families.

In the study, Dr. Fletcher and his team studied two groups of patients from 2015 to 2018. One group of 48 patients received postoperative anti-inflammatory steroids, in addition to the standard pain management treatment, and a control group of 65 patients received the standard pain management treatment. After surgery, patients self-administered opioid pain medicine through a patient-controlled anesthesia pump or pain pump. Results showed the group receiving an additional anti-inflammatory steroid utilized the pain pump 40% less often.

“The goal of any pain management protocol is to minimize the number of opioids or narcotics used given our ever-expanding knowledge of their associated risks,” said Dr. Fletcher. “This 40% decrease in pain medicine requirements means that patients are drastically more comfortable after surgery and that their risk of significant opioid use is dramatically diminished.”

This group was also almost two times more likely to walk during their initial physical therapy evaluation. Dr. Fletcher indicated that over the past 10 years, orthopedic experts have been urging kids to get up and walk sooner to help them ambulate better, which alleviates pain by reducing stiffness. He points out that for teens with scoliosis needing surgery, adding a steroid accelerates this process.

Other benefits included a decline in hospital stay from what is often as long as one week to two days, a decrease in postoperative GI complications and overall improvement in cognition. Adding steroids did not increase wound-healing problems. A reduction in pain medication gave patients the ability to become functionally independent faster and return to activities like homework more quickly, also allowing parents to resume work more quickly.

“The focus of our research is optimizing post-operative care,” said Dr. Fletcher. “Families sometimes think their kids are going to be in bed for six months, and that’s just not the case anymore. Most of our patients are back at school within a few weeks and can return to sports in a few months.”

Dr. Fletcher’s research team included Robert W. Bruce, MD and Joshua S. Murphy, MD, both orthopedic surgeons at Children's; Thomas M. Austin, MD, an anesthesiologist at Children's; Ndeye Guisse, an Emory University medical student; and Tracy Ruska, an Orthopedic Nurse Practitioner at Children's.

The findings of this study are available in the Journal of Bone and Joint Surgery

U.S. News & World Report ranks the Orthopaedics and Sports Medicine Center at Children’s No. 10 nationwide. In 2019, the center performed 482 pediatric spinal fusions, making Children’s No. 1 in volumes with a shorter average length of stay for spine procedures than most children’s hospitals in the country, according to PHIS. The center continues to perform the highest number of spine surgeries in Georgia, according to Georgia Hospital Association (GHA) data.

Pediatric Health Information System (2019) is prepared by the Children’s Hospital Association. This report compares clinical data annually for more than 52 pediatric hospitals in the U.S.

About Children’s Healthcare of Atlanta

As the only freestanding pediatric healthcare system in Georgia, Children’s Healthcare of Atlanta is the trusted leader in caring for kids. The not-for-profit organization’s mission is to make kids better today and healthier tomorrow through more than 60 pediatric specialties and programs, top healthcare professionals, and leading research and technology. Children’s is one of the largest pediatric clinical care providers in the country, managing more than one million patient visits annually at three hospitals, Marcus Autism Center, the Center for Advanced Pediatrics, urgent care centers and neighborhood locations. Consistently ranked among the top children’s hospitals by U.S. News & World Report, Children’s Healthcare of Atlanta has impacted the lives of kids in Georgia, across the United States and around the world for more than 100 years thanks to generous support from the community.

About Emory University School of Medicine

About Emory University School of Medicine
Emory University School of Medicine is a leading institution with the highest standards in education, biomedical research and patient care, with a commitment to recruiting and developing a diverse group of students and innovative leaders. Emory School of Medicine has more than 3,400 full- and part-time faculty, 592 medical students, 497 allied health students in five programs, 1,388 residents and fellows in 115 accredited programs, and 92 MD/PhD students. Medical school faculty received $588.4 million in external research funding in fiscal year 2022. The school is best known for its research and treatment in infectious disease, brain health, heart disease, cancer, transplantation, orthopaedics, pediatrics, renal disease, ophthalmology and geriatrics.

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