Scientific Publications and Presentations

Publications

Cancer and Blood Disorders

Bakshi, N., Smith, M. E., Ross, D. and Krishnamurti, L. (2017). Novel Metrics in the Longitudinal Evaluation of Pain Data in Sickle Cell Disease. The Clinical Journal of Pain, 33(6), 517-527. doi:10.1097/ajp.0000000000000431

Bakshi, N., Lukombo, I., Shnol, H., Belfer, I. and Krishnamurti, L. (2017). Psychological Characteristics and Pain Frequency Are Associated with Experimental Pain Sensitivity in Pediatric Patients with Sickle Cell Disease. The Journal of Pain. doi:10.1016/j.jpain.2017.05.005

, Fay M., Sakurai Y., McFarland B., Blanche S., Diprete C., Joiner C.H., Sulchek T. and Lam W.A. (2017) Normal Saline is Associated with Increased Sickle Red Cell Stiffness and Prolonged Transit Times in a Microfluidic Model of the Capillary System. Microcirculation. doi: 10.1111/micc.12353. [Epub ahead of print]

Dampier, C., Palermo, T.M., Darbari, D.S., Hassell, K., Smith, W. and Zempsky, W. (2017) AAPT Diagnostic Criteria for Chronic Sickle Cell Disease Pain; Journal of Pain 2017. doi: 10.1016/j.jpain.2016.12.016.

Liu W., Yu W.M., Zhang J., Chan R.J., Loh M.L., Zhang Z., Bunting K.D. and Qu, C.K. (2017) Inhibition of the Gab2/PI3K/mTOR signaling ameliorates the myeloid malignancy caused by Ptpn11 (Shp2) gain-of-function mutations. Leukemia. In press.

Mannino R.G., Santiago-Miranda A.N., Pradhan P., Qiu Y., Mejias J.C., Neelapu S.S., Roy K. and Lam W.A. (2017) 3D microvascular model recapitulates the diffuse large B-cell lymphoma tumor microenvironment in vitro. Lab on a Chip, 17(3), 407-414. doi: 10.1039/c6lc01204c

Myers D.R., Qiu Y., Fay M.E., Tennenbaum M., Chester D., Cuadrado J., Sakurai Y., Baek J., Tran R., Ciciliano J.C., Ahn B., Mannino R.G., Bunting S.T., Bennett C., Briones M., Fernandez-Nieves A., Smith M.L., Brown A.C., Sulchek T. and Lam W.A.(2017) Single-platelet nanomechanics measured by high-throughput cytometry. Nature Materials, 16(2), 230-235. doi: 10.1038/nmat4772. PMID: 27723740

O’Leary H.A.,  Capitano M., Cooper S.,  Mantel C., Boswell H.S., Kapur R., Ramdas B., Chan R., Deng L., Qu C.K., and  H.E. Broxmeyer. (2017) DPP4 Truncated GM-CSF & IL-3 Manifest Distinct Receptor Binding and Regulatory Functions Compared to their Full Length Forms. Leukemia. 2017. In press.

Quarmyne M.O., Dong W., Theodore R., Anand S., Barry V., Adisa O., Buchanan I.D., Bost J., Brown R.C., Joiner C.H. and Lane P.A. (2017) Hydroxyurea effectiveness in children and adolescents with sickle cell anemia: A large retrospective, population-based cohort. American Journal of Hematology, 92(1), 77-81. doi: 10.1002/ajh.24587. Epub Nov. 18, 2016. PMID: 27761932

Siegel D.A., Claridy M., Mertens A., George E., Vangile K., Simoneaux S.F., Meacham L.R. and Wasilewski-Masker K. (2017) Risk factors and surveillance for reduced bone mineral density in pediatric cancer survivors. Pediatric Blood & Cancer. doi: 10.1002/pbc.26488. [Epub ahead of print]

Cardiology

Q1 Publications: January-March 2018

Jeffery B. Anderson, Devyani Chowdhury, Jean A. Connor, Curt J. Daniels, Craig E. Fleishman, Michael Gaies, Jeffrey Jacobs, John Kugler, Nicolas Madsen, Robert H. Beekman, Stacey Lihn, Kay Stewart-Huey, Robert Vincent and Robert Campbell. Optimizing patient care and outcomes through the congenital heart center of the 21st century. Cong Heart Dis. 2018 Feb 5. doi: 10.1111/chd.12575. [Epub ahead of print]

Kanaan U and Mahle WT. New Paradigms for Pulmonary Vein Stenosis Treatment: When Surgery and Transcatheter Therapy Aren't Good Enough [editorial]. Journal of Pediatrics - www.jpeds.com 15March 2018

Shahanavaz S, Qureshi AM, Levi DS, Boudjemline Y, Peng LF, Martin MH, Bauser-Heaton H, Keeshan B, Asnes JD, Jones TK, Justino H, Aboulhosn JA, Gray RG, Nguyen H, Balzer DT, McElhinney DB. Transcatheter Pulmonary Valve Replacement With the Melody Valve in Small Diameter Expandable Right Ventricular Outflow Tract Conduits. JACC Cardiovasc Interv. 2018 Mar 26;11(6):554-564.

Ligon RA, Kim DW, Vincent RN, Bauser-Heaton HD, Ooi YK, Petit CJ. Angiographic follow-up of infants and children undergoing percutaneous carotid artery interventions. Catheter Cardiovasc Interv. 2018 Jan 23. doi: 10.1002/ccd.27481. [Epub ahead of print]

Bauser-Heaton H, Borquez A, Asija R, Wise-Faberowski L, Zhang Y, Downey L, Perry SB, Koth A, Peng LF, Algaze CA, Hanley FL, McElhinney DB. Pulmonary reinterventions after complete unifocalization and repair in infants and young children with tetralogy of Fallot with major aortopulmonary collaterals. J Thorac Cardiovasc Surg. 2018 Apr;155(4):1696-1707.

Chow EJ, Chen Y, Hudson MM, Feijen EAM, Kremer LC, Border WL, Green DM, Meacham LR, Mulrooney DA, Ness KK, Oeffinger KC, Ronckers CM, Sklar CA, Stovall M, van der Pal HJ, van Dijk IWEM, van Leeuwen FE, Weathers RE, Robison LL, Armstrong GT, Yasui Y. Prediction of Ischemic Heart Disease and Stroke in Survivors of Childhood Cancer. J Clin Oncol. 2018 Jan 1;36(1):44-52.

Minich LL, Pemberton VL, Shekerdemian LS, Millar MM, Newburger JW, Glatz AC, Graham EM, Czosek RJ, Pasquali SK, Seed M, Border WL. The Pediatric Heart Network Scholar Award programme: a unique mentored award embedded within a multicentre network. Cardiol Young. 2018 Apr 16:1-8.

Hales-Kharazmi A, Hirsch N, Kelleman M, Slesnick T, Deshpande SR. Utility of cardiac MRI in paediatric myocarditis. Cardiol Young. 2018 Mar;28(3):377-385.

Deshpande SR, Carroll MM, Mao C, Mahle WT, Kanter K. Biventricular support with HeartWare ventricular assist device in a pediatric patient. Pediatr Transplant. 2018 Feb;22(1).

Ellepola CD, Knight LM, Fischbach P, Deshpande SR. Genetic Testing in Pediatric Cardiomyopathy. Pediatr Cardiol. 2018 Mar;39(3):491-500.

St Louis JD, McCracken CE, Turk EM, Hancock HS, Menk JS, Harvey BA, Vinocur JM, Oster ME, Moller JH, Spector LG, Kochilas LK. Long-Term Transplant-Free Survival After Repair of Total Anomalous Pulmonary Venous Connection. Ann Thorac Surg. 2018 Jan;105(1):186-192.

Thammineni K, Vinocur JM, Harvey B, Menk JS, Kelleman MS, Korakiti AM, Thomas AS, Moller JH, St Louis JD, Kochilas LK. Outcomes after surgical coronary artery revascularisation in children with congenital heart disease. Heart. 2018 Feb 22. pii: heartjnl-2017-312652. doi: 10.1136/heartjnl-2017-312652. [Epub ahead of print]

Mahle WT, Hu C, Trachtenberg F, Menteer J, Kindel SJ, Dipchand AI, Richmond ME, Daly KP, Henderson HT, Lin KY, McCulloch M, Lal AK, Schumacher KR, Jacobs JP, Atz AM, Villa CR, Burns KM, Newburger JW; Pediatric Heart Network Investigators. Heart failure after the Norwood procedure: An analysis of the Single Ventricle Reconstruction Trial. J Heart Lung Transplant. 2018 Feb 16. pii: S1053-2498(18)31359-7. doi: 10.1016/j.healun.2018.02.009. [Epub ahead of print]

Agrawal H, Petit CJ, Miro J, Miranda CD, Kenny D, Justino H. Contralateral Pulmonary Hypertension Following Resuscitation of Unilateral Ductal Origin of a Pulmonary Artery: A Multi-institutional Review. Pediatr Cardiol. 2018 Jan;39(1):71-78.

Glatz AC, Petit CJ, Goldstein BH, Kelleman MS, McCracken CE, McDonnell A, Buckey T, Mascio CE, Shashidharan S, Ligon RA, Ao J, Whiteside W, Wallen WJ, Metcalf CM, Aggarwal V, Agrawal H, Qureshi AM. Comparison Between Patent Ductus Arteriosus Stent and Modified Blalock-Taussig Shunt as Palliation for Infants With Ductal-Dependent Pulmonary Blood Flow: Insights From the Congenital Catheterization Research Collaborative. Circulation. 2018 Feb 6;137(6):589-601.

Schwartz I, McCracken CE, Petit CJ, Sachdeva R. Late outcomes after the Fontan procedure in patients with single ventricle: a meta-analysis. Heart. 2018 Mar 13. pii: heartjnl-2017-312807. doi: 10.1136/heartjnl-2017-312807. [Epub ahead of print]

Rodriguez FH 3rd, Ephrem G, Gerardin JF, Raskind-Hood C, Hogue C, Book W. The 745.5 issue in code-based, adult congenital heart disease population studies: Relevance to current and future ICD-9-CM and ICD-10-CM studies. Congenit Heart Dis. 2018 Jan;13(1):59-64.

Rigsby CK, McKenney SE, Hill KD, Chelliah A, Einstein AJ, Han BK, Robinson JD, Sammet CL, Slesnick TC, Frush DP. Radiation dose management for pediatric cardiac computed tomography: a report from the Image Gently 'Have-A-Heart' campaign. Pediatr Radiol. 2018 Jan;48(1):5-20.

Q2 Publications: April-June 2018

Jones S, McCracken C, Alsoufi B, Mahle WT, Oster ME. Association of Pre-Operative Cell Counts With Outcomes after Surgery for Congenital Heart Disease. Ann Thorac Surg. 2018 May 10. pii: S0003-4975(18)30648-9. doi: 10.1016/j.athoracsur.2018.04.022. [Epub ahead of print]

Newburger JW, Sleeper LA, Gaynor JW, Hollenbeck-Pringle D, Frommelt PC, Li JS, Mahle WT. Circulation. 2018 May 22;137(21):2246-2253. doi: 10.1161/CIRCULATIONAHA.117.029375. Epub 2018 Feb 1.

Semmel ES, Dotson VM, Burns TG, Mahle WT, King TZ. Posterior Cerebellar Volume and Executive Function in Young Adults With Congenital Heart Disease. J Int Neuropsychol Soc. 2018 May 30:1-10. doi: 10.1017/S1355617718000310. [Epub ahead of print

Menon SC; Al-Dulaimi R, McCrindle BW, Goldberg DJ, Sachdeva R,Goldstein B, Seery T, Uzark KC, Chelliah A, Butts R, Henderson H, Johnson T, Williams RV. Delayed Puberty and Abnormal Anthropometry and its Associations with Quality of Life in Young Fontan Survivors: A Multicenter Cross-sectional Study Congenit Heart Dis. 2018 May;13(3):463-469.

Abarbanell G, Border, WL, Schlosser B, Morrow G, Kelleman MS, Sachdeva R.Preoperative Echocardiographic Measures in Interrupted Aortic Arch: Which Ones Best Predict Surgical Approach and Outcome?" Congenit Heart Dis. 2018 May;13(3):476-482.

Ramachandran P, Khoury PR, Beekman RH, Michelfelder EC, Manning PB, Tweddell JS, Cnota JF. Preoperative Aortic Arch Size and Late Outcome Following Coarctation Repair via Lateral Thoracotomy. Ann Thorac Surg 2018 May (epub ahead of print)

Concussion

Recent Publications 

Murdaugh, D., Ono, K.E., Morris S., Burns, T.G. (2018). Effects of Developmental Age on Symptom Reporting and Neurocognitive Performance in Youth After Sports-Related Concussion Compared to Control Athletes.

Murdaugh, D., Ono, K.E., Reisner, A., Burns, T.G. (2018). Assessment of Sleep Quantity and Sleep Disturbances During Recovery from Sports-Related Concussion in Young Athletes. Archives of Physical Medicine and Rehabilitation.

Reisner, A, Burns, T.G., Hall, L.B., Jain, S., Weselman, B.C., De Grauw, T.J., Ono, K.E., Blackwell, L., Chern, J.J. (2017). Quality Improvement in Concussion Care: Influence of Guideline-Based Education, The Journal of Pediatrics, 2017 May;184:26-31. doi: 10.1016/j.jpeds.2017.01.045. Epub 2017 Feb 21. PMID: 28233546

Keith H. May, P.T., D.P.T., S.C.S., A.T.C., C.S.C.S., David L. Marshall, M.D., Thomas G. Burns, Psy.D., ABPP/CN, David M. Popoli, M.D., John A. Polikandriotis, Ph.D., MBA, MPH, FACHE. Pediatric sports specific return to play guidelines following concussion. International Journal of Sports Physical Therapy, 9(2), pp. 242-255.

David Popoli, M.D., Thomas G. Burns, Psy.D., ABPP/CN, Meehan WP 3rd, Andrew Reisner, M.D. CHOA concussion consensus: establishing a uniform policy for academic accommodations. Clinical Pediatrics. 2014 Mar;53(3):217-24. doi: 10.1177/0009922813499070. Epub 2013 Aug 19.

Andrew Reisner, M.D., F.A.C.S., F.A.A.P.; Natalie Tillman, R.N., B.S.N.; Linda Cole, R.N.; Elizabeth Atkins, R.N.; Greg Pereira, R.N., B.S.N., M.B.A., Mary Thacher, R.N., MSN, CEN. Concussion in Children. Neuro Update Vol 5, Issue 1, 2011. Dr. Reisner and the Children’s concussion team take a look at the history of concussions and provide insight into the definitions, guidelines and treatments for a condition that affects millions of children each year.

Download all concussion publications and presentations

Neurology

Language and social functioning in children and adolescents with epilepsy. Byars AW, DeGrauw TJ, Johnson CS, Perkins SM, Fastenau PS, Dunn DW, Austin JK. Epilepsy Behav. 2014 Feb;31:167-71. doi: 10.1016/j.yebeh.2013.11.007. Epub 2014 Jan 14

Neuropsychology

Howarth, R.A., Reisner, A., Chern, J., Hayes, L., Burns, T.G., & Berenstein, A. (2015). Neurocognitive improvements following endovascular repair for Vein of Galen arteriovenous malformation in childhood: A case report. Journal of Neurosurgery: Pediatrics, 15, 197-202.

Burns, T.G. & Loring, D.W (2015). Psychological and social impact of epilepsy: pediatric and adolescent review. Journal of Pediatric Epilepsy, 4(3), pp. 1-7.

Reisner, A., Popoli, D.M., Burns, T.G., Marshall, D.L., Jain, S., Hall, L., Vova, J.A., Kroll, S., Wesselman, B.C., Palasis, S., Hayes, L., Clark, G., Speake, K.M., Holbrook, B.H., Wiskind, R.H., Licata, R.M., Ono, K.E., Hogan, E., Chern, J., DeGrauw, T. (2015). The Central Role of Community Practicing Pediatricians in Contemporary Concussion Care: A Case Study of CHOA’s Concussion Program. Clinical Pediatrics, pp. 1-7

Bodin, D., Roper, B., O’Toole, K., & Haines, M.E. (2015). Postdoctoral training in clinical neuropsychology: A review of the history, trends, and current issues. Training and Education in Professional Psychology.

McManus, S. & O’Toole, K. (2014). Book Review: Language Disorders in Children and Adolescents, by Joseph H. Beitchman & Elizabeth B. Brownlie. Child Neuropsychology. Published online: 23 May, 1-3.

Howarth, R.A., Adamson, A.M., Ashford, J.M., Merchant, T.E., Ogg, R.J., Schulenberg, S.E., Ogg, S., Li, J., Wu, S., Xiong, X, & Conklin, H.M. (2014). Investigating the relationship between COMT polymorphisms and working memory performance among childhood brain tumor survivors. Pediatric Blood & Cancer, 61, 40-45.

Jackson, S., Patay, Z., Howarth, R.A., Panandiker, A.S., Onar-Thomas, A., Gajjar, A., & Broniscer, A. (2013). Clinico-radiologic characteristics and neurocognitive assessment of long-term survivors of diffuse intrinsic pontine glioma. Journal of Neuro-Oncology, 114, 339-344.

Howarth, R.A., Ashford, J.M., Merchant, T.E., Ogg, R.J., Santana, V., Wu, S., Xiong, X., & Conklin, H.M. (2013). The utility of parent report in the assessment of working memory among childhood brain tumor survivors. Journal of the International Neuropsychological Society, 19, 380-389.

Alriksson-Schmidt, A.I., Thibadeau, J.K., Swanson, M.E., Marcus, D., Carris, K.L., Siffel, C., Ward, E., (2013). The Natural History of Spina Bifida in Children Pilot Project: A Research Protocol. JMIR Research Protocols (2013)

Sun, B., Berl, M.M., Burns, T.G., Gaillard, W.D., Hayes, L., Adjouadi, M., & Jones, R.A (2013). Age Association of Language Task Induced Deactivation Induced in a Pediatric Population. Neuroimage, 65, 232-33.

Burns, T.G., King, T.Z., & Spencer, K.S. (2012). Mullen Scales of Early Learning: The Utility in Assessing Children with Autism Spectrum Disorders, Cerebral Palsy, and Epilepsy. Journal of Applied Neuropsychology: Child, 1, pp. 1-10.

Sun, B., Brown, R.C., Hayes, L., Burns, T.G., Huamani, J., Bearden, D.J., & Jones, R.A. (2012). White matter damage in asymptomatic patients with sickle cell anemia: Screening with diffusion tensor imaging. American Journal of Neuroradiology, 33, pp. 1-7.

Burns, T.G. (2012). Book Review: Sherman, E.M.S., & Brooks, B.L. (Eds). (2012). Pediatric forensic Neuropsychology. New York, NY: Oxford University Press. Applied Neuropsychology: Child, (In press)

Christopher, G. & O’Toole, K. (2012). Book Review: Barkley, Russell. Executive Functions. New York: Guilford Press. “The chasm cries out for a bridge.” Child Neuropsychology, iFirst, 1-4.

Micklewright, J.L., King, T.Z., O’Toole, K., Henrich, C., & Floyd, F.J. (2012). Authoritarian Parenting Partially Mediates the Relationship between Parental Stress and Child Adaptive Outcomes 12-36 Months Following Traumatic Brain Injury. Journal of the International Neuropsychological Society, 18, 1-8.

Conklin, H.C., Ashford, J.A., Howarth, R.A., Merchant, T.E., Ogg, R.J., Santana, V., et al. (2012). Working memory performance among childhood brain tumor survivors. Journal of the International Neuropsychological Society, 18, 996-1005.

Neurosurgery

Read selected journal articles authored/co-authored by our surgeons available at PubMed, the online database provided by the U.S. National Library of Medicine National Institutes of Health publications:

View more on PubMed

Return to system within 30 days of discharge following pediatric shunt surgery. Joshua J. Chern, M.D., Ph.D., Markus Bookland, M.D., Javier Tejedor-Sojo, M.D., Jonathan Riley, M.D., Mohamm adali M. Shoja, M.D., R. Shane Tubb s, Ph.D., P.A.-C., and Andrew Reisner, M.D. J Neurosurg: Pediatrics / March 14, 2014 DOI: 10.3171/2014.2.PEDS13493

Guiding intracortical brain tumour cells to an extracortical cytotoxic hydrogel using aligned polymeric nanofibres. Anjana Jain, Martha Betancur, Gaurangkumar D. Patel, Chandra M. Valmikinathan, Vivek J. Mukhatyar, Ajit Vakharia, S. Balakrishna Pai, Barunashish
Brahma, Tobey J. MacDonald & Ravi V. Bellamkonda. Nature Materials 13, 308–316 (2014) doi:10.1038/nmat3878. Published online 16 February 2014

Aguilera, Flamini, Boydston, et al; Response of subependymal giant cell astrocytoma with spinal cord mestasis to everolimus. Journal of Pediatric Hematology/Oncology

Reisner A, Gary MF, Chern JJ, D Grattan-Smith: Spinal cord infarction following minor trauma in children; Fibrocartilaginous embolism as a putative cause: J Neurosurgery: Pediatrics, April Vol 11, 445-450, 2013.

Kebriaei MA, Shoa MM, Salinas SM, Falkenstrom KL, Sibnick, EA, Tubbs RS, Reisner A,Chern JJ; Shunt infection in the first year of life. Journal of Neurosurgery: Pediatrics July 12:44-48, 2013.

David M. Popoli, MD, Thomas Burns, PhD, William Meehan III, MD, Andrew Reisner, MD. CHOA Concussion Consensus: Establishing a Uniform Policy for Academic Accomodations. J Pediatrics (accepted)

A Heads up on Craniosynostosis, Andrew Reisner, M.D., William R. Boydston, M.D., Ph.D., Barun Brahma, M.D.; Joshua Chern, M.D., Ph.D., David Wrubel, M.D.

Abnormalities of Headshape in an Infant, Andrew Reisner, M.D., William R. Boydston, M.D., Ph.D., Barun Brahma, M.D.; Joshua Chern, M.D., Ph.D., David Wrubel, M.D.

Neuro Spine Care for Kids, David Wrubel, M.D., and Barun Brahma, M.D.

The "Epidemic" of Occipital Flattening: Why It Is Happening and What To Do About It, Andrew Reisner, M.D., William R. Boydston, M.D., Ph.D., Barun Brahma, M.D.; Joshua Chern, M.D., Ph.D., David Wrubel, M.D.

Pediatric Radiosurgery and Gamma Knife, Andrew Reisner, M.D., F.A.C.S., F.A.A.P.

Low Grade Leptomeningeal Neuroepithelial Tumor, Schniederjan, et al

Evans Blue Nanocarriers Visuall Demarcate Margins of Invasive Gliomas, Roller, et al

Nanofiber Transport of Brain Tumors, Jain et al

The Use of Inside-Outside Screws for Occipitocervial Fusion in Pediatric Patients – Accepted for publication in the Journal of Neurosurgery: Pediatrics

Transient enlargement of craniopharyngioma after radiation therapy; Pattern of MRI response following radiation. Journal of Neurooncology September 2012; 109(2); 349-55

Maurice SM, Brahma B, Burnstein FD. Disappearing dermoid: Fact or Fiction? Journal of Craniofacial Surgery. May 2012; 23(3): 812-6

Nanoparticle Liposome-Imipramine Blue inhibits medulloblastoma in SmoA1 transgenic mice.

Chern JJ, Kirkman JL, Shannon CN, Tubbs RS, Stone JD, Royal SA, Oakes WJ, Rozzelle CJ, Wellons JC. Use of lumbar ultrasonography to detect occult spinal dysraphism. Journal Neurosurgery Pediatric. 9(3):274-9, 2012.

Tubbs RS, Hattab EM, Loukas M, Chern JJ, Wellons M, Wellons JC 3rd, Iskandar BJ, Cohen-Gadol AA. Histological analysis of the third ventricle floor in hydrocephalic and non hydrocephalic brains: application to neuroendocrine complications following third ventriculostomy procedures. Journal Neurosurgery Pediatrics. 9(2):178-181, 2012.

Chern JJ, Tubbs RS, Gordon AS, Donnithorne KJ, Oakes WJ. Management of Pediatric Patients with Pseudotumor Cerebri. Childs Nerv Syst. 28(4):575-578, 2012 Jan 19.

Chern JJ, Muhleman M, Tubbs RS, Miller JH, Johnston JM, Wellons JC 3rd, Blount JP, Oakes WJ, Rozzelle CJ. Clinical evaluation and surveillance imaging in children with Spina Bifida aperta and shunt-treated hydrocephalus. J Neurosurgery Pediatrics. 9(6): 621-6, 2012.

Hwang SW, Gressot LV, Chern JJ, Relyea K, Jea A. Complications of Occipital Screw Placement for Occipitolcervical Fusion in Childres. J Neurosurgery Pediatrics. 9(6); 586-93, 2012.

Tubbs RS, Chern JJ, Muhleman M, Loukas M, Shoja MM, Oakes WJ. Lateral Compressions of the Foramen Magnum with the Chiari 1 Malformation: case illustrations. Childs Nerv Syst Apr 19, 2012.

Tubbs RS, Muhleman M, McClugage SG, Loukas M, Miller JH, Chern JJ, Rozzelle CJ, Oakes WJ, Cohen-Gadol AA. Progressive symptomative increase in the size of choroidal fissure cysts. J Neurosurg Pediatr 10(4):306-9, 2012.

Chern JJ, Aksut B, Kirkman JL, Shoja MM, Tubbs RS, Royal SA, Wellons JC 3rd, Rozzelle CJ. The accuracy of abnormal lumbar sonography findings in detecting occult spinal dysraphism: a comparison with magnetic resonance imaging. J Neurosurg Pediatr. 10(2): 150-3, 2012.

Kebriaei MA, Shoa MM, Salinas SM, Falkenstrom KL, Sibnick, EA, Tubbs RS, Reisner a. Chern JJ; Shunt infection in the first year of life. Journal of Neurosurgery: Pediatrics July 12:44-48, 2013.

Chern JJ. Response, Spinal dysraphism. J Neurosurg Pediatr. 11(5): 613, 2013.

Tubbs RS, Mortazavi MM, Farrington WJ, Chern JJ, Shoja MM, Loukas M, Cohen-Gadol AA. Relationships between the posterior interosseous nerve and the supinator muscle: application to peripheral nerve compression syndromes and nerve transfer procedures. J Neurol Surg A Cent Eur Neurosurg, 2013 May 21.

Reisner A, Gary MF, Chern JJ, D Grattan-Smith: Spinal cord infarction following minor trauma in children; Fibrocartilaginous embolism as a putative cause: J Neurosurgery: Pediatrics, April Vol 11, 445-450, 2013.

Rizk E, Chern JJ, tagayun C, Tubbs RS, Hankinson T, Rozzelle CJ, Oakes WJ, Blount JP, Wellons JC. Institutional experience of endoscopic suprasellar arachnoid cyst fenestration. Childs Nerv Syst Jan 24, 2013.

Shoja MM, Chern JJ. Letter to the editor: Decompressive craniectomy. J Neurosurg Pediatr 11(3): 358, 2013.

Orthopaedics

2017 

Murphy JS, Upasani VY, Yaszay B, et al. Predictors of distal adding-on in thoracic major curves with AR lumbar modifiers. Spine 2017;42(4).

Fuller CT, Farnsworth CL, Murphy JS. Femoral version: comparison among advanced imaging methods. J Orthop Res 2017.

Willimon SC, Busch MT, Herzog MM. Time to return to school following 10 common orthopaedic surgeries among children and adolescents.
J Pediatr Orthop 2017.

Li Y, Donohue KS, Willimon SC, et al. Reliability of radiographic assessments of adolescent midshaft clavicle fractures by the FACTS multicenter study group.
J Orthop Trauma 2017;31(9):479-484.

Pennock AT, Willimon SC, Busch MT, et al. Adolescent clavicle nonunions: potential risk factors and surgical management. 
J Shoulder Elbow Surg 2017.

Herzog MM, Busch MT, Willimon SC, et al. Functional outcomes following non-operative versus operative treatment of clavicle fractures in adolescents.
J Child Orthop 2017;11:310-317.

Pennock AT, Ellis HB, Willimon SC, et al. Intra-articular physeal fractures of the distal femur: a frequently missed diagnosis in adolescent athletes.
Orthop J Sports Med 2017;5(10).

2016 

Neumann JA, Mannava S, Busch MT, et al. Arthroscopic debridement of pediatric accessory anterolateral talar facet causing impingement.
Arthrosc Tech 2016;5(3):413-417.

Sugimoto D, Christino MA, Micheli LJ. Effects of surgical intervention on trochlear remodeling in pediatric patients with recurrent patella dislocation cases.
J Pediatr Orthop B 2016;25(4):349-353.

Christino MA, Fleming BC, Machan JT, et al. Psychological factors associated with anterior cruciate ligament reconstruction recovery.
Orthop J Sports Med 2016;4(3).

Sugimoto D, Christino MA, Micheli LJ. Effects of surgical intervention on trochlear remodeling in pediatric patients with recurrent patellar dislocation cases.
J Pediatr Orthop B 2016;25(4):349-353.

Reaume J, Reaume D, Christino MA. Psychological aspects of ACL rehabilitation. Lower Extremity Review Magazine 2016.

Heyworth BE, Christino MA. Anterior cruciate ligament tears in skeletally immature athletes. Orthopaedic Knowledge Update Sports Medicine, ed 5. Rosemont, IL: American Academy of Orthopaedic Surgeons. 2016.

Christino MA, Mansuripur PK, Hayda R. Trauma. Comprehensive board review in orthopedic surgery. New York, NY: Thieme. 2016.

Schmitz, ML. and Giavedoni, BJ. Congenital longitudinal deficiencies of the fibula. AAOS Atlas of Amputations and Limb Deficiencies- Surgical, Prosthetic, and Rehabilitation Principles, 4th Ed 2016;Chapter 73:865-872

Schrader T, Jones CR, Kaufman AM, et al. Intraoperative monitoring of epiphyseal perfusion in slipped capital femoral epiphysis. J Bone Joint Surg Am 2016;98(12):1030-1040.

Willimon SC, Gaskill TR, Millett PJ. Acromioclavicular joint injuries: anatomy, diagnosis, and treatment. Phys Sports Med 2016;39(1):116 – 122.

Herzog MM, Axelrod JR, Willimon SC, et al. Functional outcomes following nonoperative versus operative treatment of clavicle fractures in adolescents. Pediatrics 2016;137(3).

Siegall E, Willimon SC, Busch MT, et al. Age predicts disruption of the articular surface of the femoral condyles in knee OCD: Can we reduce usage of the arthroscopy and MRI? J Pediat Ortho 2016.

2015

Truntzer J, Vopat ML, Christino MA, et al. Forearm diaphyseal fractures in the adolescent population: treatment and management. Eur J Orthop Surg Traumatol 2015;25(2):201-209.

Christino MA, Vopat BG, Mayer A, et al. Stability outcomes following computer-assisted ACL reconstruction. Minimally Invasive Surgery 2015.

Vopat BG, Daniels AH, Christino MA, et al. Hybrid anterolateral approach for open reduction internal fixation of femoral neck fractures.
Orthopedics 2015;38(7):430-434.

Christino MA, Fantry A, Vopat BG. Psychological aspects of recovery following anterior cruciate ligament reconstruction. J Am Acad Orthop Surg 2015;23(8):501-509. 

Murphy JS, Mubarak SJ. Talocalcaneal coalitions. Foot Ankle Clin. 2015;20(4):681-91.

Wilcox, WR, Coulder, CP, Schmitz, ML. Congenital limb deficiencies. Clinics in Perinatology 42:281-300, 2015

Schrader T, Ward WT. Pericapsular osteotomies of pemberton and dega. In Wiesel S (Ed), Operative Techniques in Orthopaedic Surgery: 1924-1933. 2015.

Hyman JE, Trupia, Schrader T, et al. Interobserver and intraobserver reliability of the modified Waldenstrom classification system for staging of Legg-Calve-Perthes disease.
J Bone Joint Surg 2015;97(8):643-650.

Willimon SC, Jones CR, Herzog MM, May KH, Leake MJ, Busch MT. Micheli anterior cruciate ligament reconstruction in skeletally immature youths: A retrospective case series with a mean 3-year follow-up. Am J Sports Med 2015;43(12): 2974-2981.

  • This study is to evaluate the clinical outcomes of a physeal-sparing technique using the illotibial band for combined intra-articular and extra-articular ACL reconstruction. At a mean 3-year follow-up, the study findings confirmed excellent functional outcomes, a low ACL revision rate, and no growth disturbances.

McLaren K, Byrd E, Willimon, SC, et al. Impact shoulder angles correlate with impact wrist angles in standing back handsprings in preadolescent and adolescent female gymnasts.
International journal of sports physical therapy 2015;10(3).

Steadman JR, Briggs KK, Willimon SC, et al. Outcomes following microfracture of full-thickness articular cartilage lesions of the knee in adolescent patients.
Journal of Knee Surgery 2015;28(2):145-150.

2014

Archibald-Seiffer N, Weiss J, Busch MT. Cases and current concepts in pediatric sports medicineJ Pediatr Orthop 2014;34:S49-S56.

Christino MA, Vopat BG, Waryasz GR, et al. Adolescent differences in knee stability following computer-assisted ACL reconstruction.
Orthopedic Reviews 2014;6(4).

Vopat ML, Kane PM, Christino MA, et al. Treatment of forearm fractures in children.
Orthopedic Reviews 2014;6(2).

Fletcher ND, Shourbaji N, Devito DP, et al. Clinical and economic implications of early discharge following posterior spinal fusion for adolescent idiopathic scoliosis.
J Child Orthop 2014;8(3):257-263.

Willimon SC, Briggs, KK, Philippon MJ. Intra-articular adhesions following hip arthroscopy: a risk factor analysis. Knee Surgery, Sports Traumatology Arthroscopy 2014;22(4):822-825.

2013

Garrigues GE, Warnick DE, Busch MT. Subscapularis avulsion of the lesser tuberosity in adolescent. J Pediatr Orthop. 2013;33(1):8-13. [PMID 23232372]

  • This study is a long-term clinical follow-up study of patients with isolated lesser tuberosity avulsions in skeletally immature patients. Operative treatment consisted of a diagnostic arthroscopy to evaluate for concomitant pathology, followed by an open reattachment of the tuberosity through an incision in line with the anterior axillary fold.

PI: Michael Schmitz, M.D., National Institutes of Health

The BrAIST study is a Phase III, multicenter, prospective partially-randomized, partially blinded clinical trial, designed to determine whether the use of the thoracolumbosacral orthoses (brace) lowers the risk of curve progression in patients with adolescent idiopathic scoliosis (AIS) relative to observation (watchful waiting).

Weinstein SL, Dolan LA, Wright JG, Dobbs MB. Effects of bracing in adolescents with idiopathic scoliosis. N Engl J Med. 2013;369(16):1512-1521. [PMID: 23232372]

Grants

Cancer and Blood Disorders

Ben Watkins, MD, Assistant Professor at Emory University, has earned an NIH K23 grant for his work with allogeneic hematopoietic stem cell transplantation (HCT), which is an effective treatment for hematological malignancy. However, significant complications limit its widespread application. Chronic graft-versus-host disease (GVHD) is the leading cause of long-term morbidity and mortality following HCT, and recent advances have failed to reduce the frequency or severity of this devastating complication. The mechanisms of the development and evolution of chronic GVHD have not been clearly defined, thus challenging progress in the design of new therapeutic approaches aimed at preventing or treating the disease. Flow cytometry and gene expression profiling have emerged as valuable tools to interrogate complex disease states and define the molecular changes that occur during the development of disease.

The long-term approach of this work is to identify the mechanistic drivers of chronic GVHD to aid in our understanding of the disease and help elucidate targetable pathways to alter its natural history. To identify the mechanisms driving GVHD, we have developed a systems biology approach that combines longitudinal flow cytometry with gene expression analysis linked to detailed clinical data. Utilizing data from an ongoing multi-center clinical trial investigating GVHD, we will apply supervised and unsupervised approaches to determine the molecular signature of T and B cells linked to the development and evolution of chronic GVHD.