Scientific Publications and Presentations

Publications

Cancer and Blood Disorders

Cardiology

Q4 Publications: October-December 2018

Jones S, McCracken C, Alsoufi B, Mahle WT, Oster ME. Association of pre-operative cell count abnormalities with outcomes following surgery for congenital heart disease. Ann Thorac Surg. 2018 Oct;106(4):1234-1240.

Alsoufi B, McCracken C, Oster ME, Shashidharan S, Kanter K. Genetic and Extracardiac Anomalies are Associated with Inferior Single Ventricle Palliation Outcomes. Ann Thorac Surg. 2018 Oct;106(4):1204-1212.

Kiener A, Kelleman M, McCracken C, Kochilas L, St. Louis D, Oster ME. Long-term Survival following Arterial vs. Atrial Switch in d-Transposition of the Great Arteries. Annals of Thoracic Surgery. 2018 Dec;106(6):1827-1833.

Zaki NC, Kellemann MS, Parks WJ, Slesnick TC, McConnell ME, Oster ME. The Utility of Cardiac Magnetic Resonance Imaging in Post-Fontan Surveillance. Congenital Heart Disease. Congenit Heart Dis. 2018 Oct 30. doi: 10.1111/chd.12692. [Epub ahead of print]

Diallo AO, Krishnaswamy A, Shapira SK, George MG, Oster ME, Weiss P, Ali MK, Book W. Detecting Moderate or Complex Congenital Heart Defects in Adults from an Electronic Health Records System. Journal of the American Medical Informatics Association. J Am Med Inform Assoc. 2018 Dec 1;25(12):1634-1642.

Oster ME, Knight JH, Suthar D, Amin O, Kochilas LK. Long-term outcomes in single-ventricle congenital heart disease: the importance of ventricular morphology. Circulation. 2018;138:2718-2720.

Whitehill R, Fischbach P, Oster ME. Single Ventricle, Many Arrhythmias. Journal of Thoracic Disease. 2018 Nov;10(Suppl 33):S4040-S4042.

McCracken C, Spector LG, Menk J, Knight JH, Vinocur JM, Thomas A, Oster ME, St. Louis JD, Moller JH, Kochilas L. Mortality Following Pediatric Congenital Heart Surgery: An Analysis of the Causes of Death Derived from the National Death Index. J Am Heart Assoc. 2018 Nov 20;7(22):e010624.

Smith CA, McCracken C, Thomas A, Spector L, St. Louis JD, Oster ME, Moller J, Kochilas L. Long-term Outcomes of Tetralogy of Fallot: A Study from the Pediatric Cardiac Care Consortium. JAMA Cardiology. 2018 Dec 19.

Regalado ES, Mellor-Crummey L, De Backer J, Braverman AC, Ades L, Benedict S, Bradley TJ, Brickner ME, Chatfield KC, Child A, Feist C, Holmes KW, Iannucci G, Lorenz B, Mark P, Morisaki T, Morisaki H, Morris SA, Mitchell AL, Ostergaard JR, Richer J, Sallee D, Shalhub S, Tekin M; Montalcino Aortic Consortium, Estrera A, Musolino P, Yetman A, Pyeritz R, Milewicz DM. Clinical history and management recommendations of the smooth muscle dysfunction syndrome due to ACTA2 arginine 179 alterations. Genet Med. 2018 Oct;20(10):1206-1215.

Hebson CL, McConnell ME, Hannon DW. Pediatric dysautonomia: Much-maligned, often overmedicated, but not as complex as you think. Congenit Heart Dis. 2018 Nov 28. doi: 10.1111/chd.12720. [Epub ahead of print]

Ooi YK, Kim SIH, Gillespie SE, Kim DW, Vincent RN, Petit CJ. Premounted stents for branch pulmonary artery stenosis in children: A short term solution. Catheter Cardiovasc Interv. 2018 Dec 1;92(7):1315-1322. doi: 10.1002/ccd.27800. Epub 2018 Sep 9.

Concussion

Recent Publications 

Murdaugh, D., Ono, K.E., Morris S., Burns, T.G. (2018). Effects of Developmental Age on Symptom Reporting and Neurocognitive Performance in Youth After Sports-Related Concussion Compared to Control Athletes.

Murdaugh, D., Ono, K.E., Reisner, A., Burns, T.G. (2018). Assessment of Sleep Quantity and Sleep Disturbances During Recovery from Sports-Related Concussion in Young Athletes. Archives of Physical Medicine and Rehabilitation.

Reisner, A, Burns, T.G., Hall, L.B., Jain, S., Weselman, B.C., De Grauw, T.J., Ono, K.E., Blackwell, L., Chern, J.J. (2017). Quality Improvement in Concussion Care: Influence of Guideline-Based Education, The Journal of Pediatrics, 2017 May;184:26-31. doi: 10.1016/j.jpeds.2017.01.045. Epub 2017 Feb 21. PMID: 28233546

Keith H. May, P.T., D.P.T., S.C.S., A.T.C., C.S.C.S., David L. Marshall, M.D., Thomas G. Burns, Psy.D., ABPP/CN, David M. Popoli, M.D., John A. Polikandriotis, Ph.D., MBA, MPH, FACHE. Pediatric sports specific return to play guidelines following concussion. International Journal of Sports Physical Therapy, 9(2), pp. 242-255.

David Popoli, M.D., Thomas G. Burns, Psy.D., ABPP/CN, Meehan WP 3rd, Andrew Reisner, M.D. CHOA concussion consensus: establishing a uniform policy for academic accommodations. Clinical Pediatrics. 2014 Mar;53(3):217-24. doi: 10.1177/0009922813499070. Epub 2013 Aug 19.

Andrew Reisner, M.D., F.A.C.S., F.A.A.P.; Natalie Tillman, R.N., B.S.N.; Linda Cole, R.N.; Elizabeth Atkins, R.N.; Greg Pereira, R.N., B.S.N., M.B.A., Mary Thacher, R.N., MSN, CEN. Concussion in Children. Neuro Update Vol 5, Issue 1, 2011. Dr. Reisner and the Children’s concussion team take a look at the history of concussions and provide insight into the definitions, guidelines and treatments for a condition that affects millions of children each year.

Download all concussion publications and presentations

Neurology

Language and social functioning in children and adolescents with epilepsy. Byars AW, DeGrauw TJ, Johnson CS, Perkins SM, Fastenau PS, Dunn DW, Austin JK. Epilepsy Behav. 2014 Feb;31:167-71. doi: 10.1016/j.yebeh.2013.11.007. Epub 2014 Jan 14

Neuropsychology

Howarth, R.A., Reisner, A., Chern, J., Hayes, L., Burns, T.G., & Berenstein, A. (2015). Neurocognitive improvements following endovascular repair for Vein of Galen arteriovenous malformation in childhood: A case report. Journal of Neurosurgery: Pediatrics, 15, 197-202.

Burns, T.G. & Loring, D.W (2015). Psychological and social impact of epilepsy: pediatric and adolescent review. Journal of Pediatric Epilepsy, 4(3), pp. 1-7.

Reisner, A., Popoli, D.M., Burns, T.G., Marshall, D.L., Jain, S., Hall, L., Vova, J.A., Kroll, S., Wesselman, B.C., Palasis, S., Hayes, L., Clark, G., Speake, K.M., Holbrook, B.H., Wiskind, R.H., Licata, R.M., Ono, K.E., Hogan, E., Chern, J., DeGrauw, T. (2015). The Central Role of Community Practicing Pediatricians in Contemporary Concussion Care: A Case Study of CHOA’s Concussion Program. Clinical Pediatrics, pp. 1-7

Bodin, D., Roper, B., O’Toole, K., & Haines, M.E. (2015). Postdoctoral training in clinical neuropsychology: A review of the history, trends, and current issues. Training and Education in Professional Psychology.

McManus, S. & O’Toole, K. (2014). Book Review: Language Disorders in Children and Adolescents, by Joseph H. Beitchman & Elizabeth B. Brownlie. Child Neuropsychology. Published online: 23 May, 1-3.

Howarth, R.A., Adamson, A.M., Ashford, J.M., Merchant, T.E., Ogg, R.J., Schulenberg, S.E., Ogg, S., Li, J., Wu, S., Xiong, X, & Conklin, H.M. (2014). Investigating the relationship between COMT polymorphisms and working memory performance among childhood brain tumor survivors. Pediatric Blood & Cancer, 61, 40-45.

Jackson, S., Patay, Z., Howarth, R.A., Panandiker, A.S., Onar-Thomas, A., Gajjar, A., & Broniscer, A. (2013). Clinico-radiologic characteristics and neurocognitive assessment of long-term survivors of diffuse intrinsic pontine glioma. Journal of Neuro-Oncology, 114, 339-344.

Howarth, R.A., Ashford, J.M., Merchant, T.E., Ogg, R.J., Santana, V., Wu, S., Xiong, X., & Conklin, H.M. (2013). The utility of parent report in the assessment of working memory among childhood brain tumor survivors. Journal of the International Neuropsychological Society, 19, 380-389.

Alriksson-Schmidt, A.I., Thibadeau, J.K., Swanson, M.E., Marcus, D., Carris, K.L., Siffel, C., Ward, E., (2013). The Natural History of Spina Bifida in Children Pilot Project: A Research Protocol. JMIR Research Protocols (2013)

Sun, B., Berl, M.M., Burns, T.G., Gaillard, W.D., Hayes, L., Adjouadi, M., & Jones, R.A (2013). Age Association of Language Task Induced Deactivation Induced in a Pediatric Population. Neuroimage, 65, 232-33.

Burns, T.G., King, T.Z., & Spencer, K.S. (2012). Mullen Scales of Early Learning: The Utility in Assessing Children with Autism Spectrum Disorders, Cerebral Palsy, and Epilepsy. Journal of Applied Neuropsychology: Child, 1, pp. 1-10.

Sun, B., Brown, R.C., Hayes, L., Burns, T.G., Huamani, J., Bearden, D.J., & Jones, R.A. (2012). White matter damage in asymptomatic patients with sickle cell anemia: Screening with diffusion tensor imaging. American Journal of Neuroradiology, 33, pp. 1-7.

Burns, T.G. (2012). Book Review: Sherman, E.M.S., & Brooks, B.L. (Eds). (2012). Pediatric forensic Neuropsychology. New York, NY: Oxford University Press. Applied Neuropsychology: Child, (In press)

Christopher, G. & O’Toole, K. (2012). Book Review: Barkley, Russell. Executive Functions. New York: Guilford Press. “The chasm cries out for a bridge.” Child Neuropsychology, iFirst, 1-4.

Micklewright, J.L., King, T.Z., O’Toole, K., Henrich, C., & Floyd, F.J. (2012). Authoritarian Parenting Partially Mediates the Relationship between Parental Stress and Child Adaptive Outcomes 12-36 Months Following Traumatic Brain Injury. Journal of the International Neuropsychological Society, 18, 1-8.

Conklin, H.C., Ashford, J.A., Howarth, R.A., Merchant, T.E., Ogg, R.J., Santana, V., et al. (2012). Working memory performance among childhood brain tumor survivors. Journal of the International Neuropsychological Society, 18, 996-1005.

Neurosurgery

Read selected journal articles authored/co-authored by our surgeons available at PubMed, the online database provided by the U.S. National Library of Medicine National Institutes of Health publications:

View more on PubMed

Return to system within 30 days of discharge following pediatric shunt surgery. Joshua J. Chern, M.D., Ph.D., Markus Bookland, M.D., Javier Tejedor-Sojo, M.D., Jonathan Riley, M.D., Mohamm adali M. Shoja, M.D., R. Shane Tubb s, Ph.D., P.A.-C., and Andrew Reisner, M.D. J Neurosurg: Pediatrics / March 14, 2014 DOI: 10.3171/2014.2.PEDS13493

Guiding intracortical brain tumour cells to an extracortical cytotoxic hydrogel using aligned polymeric nanofibres. Anjana Jain, Martha Betancur, Gaurangkumar D. Patel, Chandra M. Valmikinathan, Vivek J. Mukhatyar, Ajit Vakharia, S. Balakrishna Pai, Barunashish
Brahma, Tobey J. MacDonald & Ravi V. Bellamkonda. Nature Materials 13, 308–316 (2014) doi:10.1038/nmat3878. Published online 16 February 2014

Aguilera, Flamini, Boydston, et al; Response of subependymal giant cell astrocytoma with spinal cord mestasis to everolimus. Journal of Pediatric Hematology/Oncology

Reisner A, Gary MF, Chern JJ, D Grattan-Smith: Spinal cord infarction following minor trauma in children; Fibrocartilaginous embolism as a putative cause: J Neurosurgery: Pediatrics, April Vol 11, 445-450, 2013.

Kebriaei MA, Shoa MM, Salinas SM, Falkenstrom KL, Sibnick, EA, Tubbs RS, Reisner A,Chern JJ; Shunt infection in the first year of life. Journal of Neurosurgery: Pediatrics July 12:44-48, 2013.

David M. Popoli, MD, Thomas Burns, PhD, William Meehan III, MD, Andrew Reisner, MD. CHOA Concussion Consensus: Establishing a Uniform Policy for Academic Accomodations. J Pediatrics (accepted)

A Heads up on Craniosynostosis, Andrew Reisner, M.D., William R. Boydston, M.D., Ph.D., Barun Brahma, M.D.; Joshua Chern, M.D., Ph.D., David Wrubel, M.D.

Abnormalities of Headshape in an Infant, Andrew Reisner, M.D., William R. Boydston, M.D., Ph.D., Barun Brahma, M.D.; Joshua Chern, M.D., Ph.D., David Wrubel, M.D.

Neuro Spine Care for Kids, David Wrubel, M.D., and Barun Brahma, M.D.

The "Epidemic" of Occipital Flattening: Why It Is Happening and What To Do About It, Andrew Reisner, M.D., William R. Boydston, M.D., Ph.D., Barun Brahma, M.D.; Joshua Chern, M.D., Ph.D., David Wrubel, M.D.

Pediatric Radiosurgery and Gamma Knife, Andrew Reisner, M.D., F.A.C.S., F.A.A.P.

Low Grade Leptomeningeal Neuroepithelial Tumor, Schniederjan, et al

Evans Blue Nanocarriers Visuall Demarcate Margins of Invasive Gliomas, Roller, et al

Nanofiber Transport of Brain Tumors, Jain et al

The Use of Inside-Outside Screws for Occipitocervial Fusion in Pediatric Patients – Accepted for publication in the Journal of Neurosurgery: Pediatrics

Transient enlargement of craniopharyngioma after radiation therapy; Pattern of MRI response following radiation. Journal of Neurooncology September 2012; 109(2); 349-55

Maurice SM, Brahma B, Burnstein FD. Disappearing dermoid: Fact or Fiction? Journal of Craniofacial Surgery. May 2012; 23(3): 812-6

Nanoparticle Liposome-Imipramine Blue inhibits medulloblastoma in SmoA1 transgenic mice.

Chern JJ, Kirkman JL, Shannon CN, Tubbs RS, Stone JD, Royal SA, Oakes WJ, Rozzelle CJ, Wellons JC. Use of lumbar ultrasonography to detect occult spinal dysraphism. Journal Neurosurgery Pediatric. 9(3):274-9, 2012.

Tubbs RS, Hattab EM, Loukas M, Chern JJ, Wellons M, Wellons JC 3rd, Iskandar BJ, Cohen-Gadol AA. Histological analysis of the third ventricle floor in hydrocephalic and non hydrocephalic brains: application to neuroendocrine complications following third ventriculostomy procedures. Journal Neurosurgery Pediatrics. 9(2):178-181, 2012.

Chern JJ, Tubbs RS, Gordon AS, Donnithorne KJ, Oakes WJ. Management of Pediatric Patients with Pseudotumor Cerebri. Childs Nerv Syst. 28(4):575-578, 2012 Jan 19.

Chern JJ, Muhleman M, Tubbs RS, Miller JH, Johnston JM, Wellons JC 3rd, Blount JP, Oakes WJ, Rozzelle CJ. Clinical evaluation and surveillance imaging in children with Spina Bifida aperta and shunt-treated hydrocephalus. J Neurosurgery Pediatrics. 9(6): 621-6, 2012.

Hwang SW, Gressot LV, Chern JJ, Relyea K, Jea A. Complications of Occipital Screw Placement for Occipitolcervical Fusion in Childres. J Neurosurgery Pediatrics. 9(6); 586-93, 2012.

Tubbs RS, Chern JJ, Muhleman M, Loukas M, Shoja MM, Oakes WJ. Lateral Compressions of the Foramen Magnum with the Chiari 1 Malformation: case illustrations. Childs Nerv Syst Apr 19, 2012.

Tubbs RS, Muhleman M, McClugage SG, Loukas M, Miller JH, Chern JJ, Rozzelle CJ, Oakes WJ, Cohen-Gadol AA. Progressive symptomative increase in the size of choroidal fissure cysts. J Neurosurg Pediatr 10(4):306-9, 2012.

Chern JJ, Aksut B, Kirkman JL, Shoja MM, Tubbs RS, Royal SA, Wellons JC 3rd, Rozzelle CJ. The accuracy of abnormal lumbar sonography findings in detecting occult spinal dysraphism: a comparison with magnetic resonance imaging. J Neurosurg Pediatr. 10(2): 150-3, 2012.

Kebriaei MA, Shoa MM, Salinas SM, Falkenstrom KL, Sibnick, EA, Tubbs RS, Reisner a. Chern JJ; Shunt infection in the first year of life. Journal of Neurosurgery: Pediatrics July 12:44-48, 2013.

Chern JJ. Response, Spinal dysraphism. J Neurosurg Pediatr. 11(5): 613, 2013.

Tubbs RS, Mortazavi MM, Farrington WJ, Chern JJ, Shoja MM, Loukas M, Cohen-Gadol AA. Relationships between the posterior interosseous nerve and the supinator muscle: application to peripheral nerve compression syndromes and nerve transfer procedures. J Neurol Surg A Cent Eur Neurosurg, 2013 May 21.

Reisner A, Gary MF, Chern JJ, D Grattan-Smith: Spinal cord infarction following minor trauma in children; Fibrocartilaginous embolism as a putative cause: J Neurosurgery: Pediatrics, April Vol 11, 445-450, 2013.

Rizk E, Chern JJ, tagayun C, Tubbs RS, Hankinson T, Rozzelle CJ, Oakes WJ, Blount JP, Wellons JC. Institutional experience of endoscopic suprasellar arachnoid cyst fenestration. Childs Nerv Syst Jan 24, 2013.

Shoja MM, Chern JJ. Letter to the editor: Decompressive craniectomy. J Neurosurg Pediatr 11(3): 358, 2013.

Orthopaedics

Learn about our current pediatric orthopaedic research efforts

Past publications 2013-2016

2016

Neumann JA, Mannava S, Busch MT, et al. Arthroscopic debridement of pediatric accessory anterolateral talar facet causing impingement.
Arthrosc Tech 2016;5(3):413-417.

Sugimoto D, Christino MA, Micheli LJ. Effects of surgical intervention on trochlear remodeling in pediatric patients with recurrent patella dislocation cases.
J Pediatr Orthop B 2016;25(4):349-353.

Christino MA, Fleming BC, Machan JT, et al. Psychological factors associated with anterior cruciate ligament reconstruction recovery.
Orthop J Sports Med 2016;4(3).

Sugimoto D, Christino MA, Micheli LJ. Effects of surgical intervention on trochlear remodeling in pediatric patients with recurrent patellar dislocation cases.
J Pediatr Orthop B 2016;25(4):349-353.

Reaume J, Reaume D, Christino MA. Psychological aspects of ACL rehabilitation. Lower Extremity Review Magazine 2016.

Heyworth BE, Christino MA. Anterior cruciate ligament tears in skeletally immature athletes. Orthopaedic Knowledge Update Sports Medicine, ed 5. Rosemont, IL: American Academy of Orthopaedic Surgeons. 2016.

Christino MA, Mansuripur PK, Hayda R. Trauma. Comprehensive board review in orthopedic surgery. New York, NY: Thieme. 2016.

Schmitz, ML. and Giavedoni, BJ. Congenital longitudinal deficiencies of the fibula. AAOS Atlas of Amputations and Limb Deficiencies- Surgical, Prosthetic, and Rehabilitation Principles, 4th Ed 2016;Chapter 73:865-872

Schrader T, Jones CR, Kaufman AM, et al. Intraoperative monitoring of epiphyseal perfusion in slipped capital femoral epiphysis. J Bone Joint Surg Am 2016;98(12):1030-1040.

Willimon SC, Gaskill TR, Millett PJ. Acromioclavicular joint injuries: anatomy, diagnosis, and treatment. Phys Sports Med 2016;39(1):116 – 122.

Herzog MM, Axelrod JR, Willimon SC, et al. Functional outcomes following nonoperative versus operative treatment of clavicle fractures in adolescents. Pediatrics 2016;137(3).

Siegall E, Willimon SC, Busch MT, et al. Age predicts disruption of the articular surface of the femoral condyles in knee OCD: Can we reduce usage of the arthroscopy and MRI? J Pediat Ortho 2016.

2015

Truntzer J, Vopat ML, Christino MA, et al. Forearm diaphyseal fractures in the adolescent population: treatment and management. Eur J Orthop Surg Traumatol 2015;25(2):201-209.

Christino MA, Vopat BG, Mayer A, et al. Stability outcomes following computer-assisted ACL reconstruction. Minimally Invasive Surgery 2015.

Vopat BG, Daniels AH, Christino MA, et al. Hybrid anterolateral approach for open reduction internal fixation of femoral neck fractures.
Orthopedics 2015;38(7):430-434.

Christino MA, Fantry A, Vopat BG. Psychological aspects of recovery following anterior cruciate ligament reconstruction. J Am Acad Orthop Surg 2015;23(8):501-509. 

Murphy JS, Mubarak SJ. Talocalcaneal coalitions. Foot Ankle Clin. 2015;20(4):681-91.

Wilcox, WR, Coulder, CP, Schmitz, ML. Congenital limb deficiencies. Clinics in Perinatology 42:281-300, 2015

Schrader T, Ward WT. Pericapsular osteotomies of pemberton and dega. In Wiesel S (Ed), Operative Techniques in Orthopaedic Surgery: 1924-1933. 2015.

Hyman JE, Trupia, Schrader T, et al. Interobserver and intraobserver reliability of the modified Waldenstrom classification system for staging of Legg-Calve-Perthes disease.
J Bone Joint Surg 2015;97(8):643-650.

Willimon SC, Jones CR, Herzog MM, May KH, Leake MJ, Busch MT. Micheli anterior cruciate ligament reconstruction in skeletally immature youths: A retrospective case series with a mean 3-year follow-up. Am J Sports Med 2015;43(12): 2974-2981.

  • This study is to evaluate the clinical outcomes of a physeal-sparing technique using the illotibial band for combined intra-articular and extra-articular ACL reconstruction. At a mean 3-year follow-up, the study findings confirmed excellent functional outcomes, a low ACL revision rate, and no growth disturbances.

McLaren K, Byrd E, Willimon, SC, et al. Impact shoulder angles correlate with impact wrist angles in standing back handsprings in preadolescent and adolescent female gymnasts.
International journal of sports physical therapy 2015;10(3).

Steadman JR, Briggs KK, Willimon SC, et al. Outcomes following microfracture of full-thickness articular cartilage lesions of the knee in adolescent patients.
Journal of Knee Surgery 2015;28(2):145-150.

2014

Archibald-Seiffer N, Weiss J, Busch MT. Cases and current concepts in pediatric sports medicineJ Pediatr Orthop 2014;34:S49-S56.

Christino MA, Vopat BG, Waryasz GR, et al. Adolescent differences in knee stability following computer-assisted ACL reconstruction.
Orthopedic Reviews 2014;6(4).

Vopat ML, Kane PM, Christino MA, et al. Treatment of forearm fractures in children.
Orthopedic Reviews 2014;6(2).

Fletcher ND, Shourbaji N, Devito DP, et al. Clinical and economic implications of early discharge following posterior spinal fusion for adolescent idiopathic scoliosis.
J Child Orthop 2014;8(3):257-263.

Willimon SC, Briggs, KK, Philippon MJ. Intra-articular adhesions following hip arthroscopy: a risk factor analysis. Knee Surgery, Sports Traumatology Arthroscopy 2014;22(4):822-825.

2013

Garrigues GE, Warnick DE, Busch MT. Subscapularis avulsion of the lesser tuberosity in adolescent. J Pediatr Orthop. 2013;33(1):8-13. [PMID 23232372]

  • This study is a long-term clinical follow-up study of patients with isolated lesser tuberosity avulsions in skeletally immature patients. Operative treatment consisted of a diagnostic arthroscopy to evaluate for concomitant pathology, followed by an open reattachment of the tuberosity through an incision in line with the anterior axillary fold.

PI: Michael Schmitz, M.D., National Institutes of Health

The BrAIST study is a Phase III, multicenter, prospective partially-randomized, partially blinded clinical trial, designed to determine whether the use of the thoracolumbosacral orthoses (brace) lowers the risk of curve progression in patients with adolescent idiopathic scoliosis (AIS) relative to observation (watchful waiting).

Weinstein SL, Dolan LA, Wright JG, Dobbs MB. Effects of bracing in adolescents with idiopathic scoliosis. N Engl J Med. 2013;369(16):1512-1521. [PMID: 23232372]

Grants

Cancer and Blood Disorders

Cheng-Kui Qu, M.D., Ph.D. received the Hyundai Hope on Wheels Scholar Award (PI), September 2016 to August 2018, “Targeting Shp2 phosphatase for chemoprevention of leukemic progression in Noonan Syndrome”, Direct cost: $125,000 per year

Cheng-Kui Qu, M.D., Ph.D. received NIH R01 award (PI), August 2016 to June 2020, “Germline mutations of PTPN11(SHP-2) in the stem cell microenvironment”, Director cost: $250,000 per year

Christopher Doering, Ph.D. and H. Trent Spencer, Ph.D. received NIH/NHLBI R56 award (PIs), September 2016 to August 2017, “Ancestral Sequence Reconstruction Engineering of Coagulation Factors” $255,000

Christopher Doering, Ph.D. and H. Trent Spencer, Ph.D. received NIH/NHLBI R43 award (MPI: Doering/Spencer/Denning) September 2016 to August 2017, “Lead Candidate Liver-Directed AAV-FVIII Expression Cassette” $225,000

H. Trent Spencer, Ph.D. and Christopher Doering, Ph.D. received a Hemophilia of Georgia, Inc. Research Grant (Spencer PI, Doering Co-PI), October 2016 to September 2018,  “Hematopoietic Stem Cell Gene Therapy for Hemophilia A” $437,574 per year (twice a year)

Hyacinth Hyacinth, M.D., Ph.D., MPH, Instructor of Pediatrics at Emory University, received a $225,000 grant from the NIH that will run from July 2017 through June 2022. Dr. Hyacinth is the principal investigator on the grant, which will study the mechanism of cerebral vasculopathy in sickle cell disease.

Elizabeth Stenger, M.D., Assistant Professor of Pediatrics at Emory University, received a $187,812 K23 grant from the NIH that will run from August 2016 to July 2020 for her work on improving haplo-identical stem cell transplantation in sickle cell disease using autologous mesenchymal stromal cells (MSCs).