Aflac Cancer Center and Blood Disorders Service
Nandini Dey, Ph.D.
Pediatric Hematology/Oncology
Winship Cancer Institute
Emory University
1365 Clifton Road
Building C, Room # 5054
Atlanta, GA 30322
Instructor
Emory University School of Medicine
Education/Training
Doctoral Degrees: Indian Institute of Chemical Biology, Council for Scientific and Industrial Research, Jadavpur University, Calcutta, India, (submitted in 1993 and awarded in 1996)
Master’s of Science in Physiology: Calcutta University, 1987
Fellowships: Government of India: Junior Research Fellowship, Indian Council of Medical Research, 1989-1991; Senior Research Fellowship, Center for Scientific & Industrial Research, 1991-1993; Post-Doctoral Research Fellowship, Indian Council of Medical Research, 1993-1999
Awards/Honors
- Sakuntala Amir Chand award from Indian Council of Medical Research for best publication, 1991
- Selected presentation in the Rajanikant Baxi Award, 1995
Professional/Scientific Societies
- Association of Physiology and Pharmacology of India
- Indian Association for Cancer Research
- Indian Academy of Neurosciences
Areas of Interest/Research
- Signaling events underlying the differentiation in human NB cells
- The involvement of non-receptor tyrosine kinase family, SRC in nerve growth factor (NGF) and retinoic acid (RA) - induced neuronal differentiation
- Role of kinases (SFKs) in brain tumor (GBM) progression
- Role of dual phosphatase, PTEN, in integrin directed migration of brain tumors and primary astrocytes derived from mouse model of brain tumors
- Studying the signaling events of neuronal differentiation, specifically the role of the non-receptor tyrosine kinase family, SRC, in nerve growth factor (NGF) and retinoic acid (RA) induced neuronal differentiation. Knowledge of downstream signals of differentiation following the activation of SRC will be used to design new drug targets. Better understanding of the differentiation process in neuronal cells will help to develop tools to manipulate neuronal stem cells and to study the degenerative diseases of nervous system. Also studying the role of PTEN (dual phosphatase) in migration of glioblastomas in order to know the interactions between PTEN and different tumor suppressor genes like P53 and NF (primary astrocytes and tumors) using mouse genetic models.
Publications/Presentations/Other
- Selected journal articles authored/co-authored by this researcher are available at http://www.ncbi.nlm.nih.gov/pubmed
- Author/co-author of numerous articles in peer-reviewed publications such as Brain Research Bulletin and Neurochemistry
- Has delivered presentations at international, national and local scientific conferences and meetings