Liver Transplant Research and Development

Pediatric Research
Committed to excellence and innovation in pediatric research

In conjunction with Emory University School of Medicine, the Children's Carlos and Marguerite Mason Transplant Center is committed to excellence and innovation in pediatric liver transplant research.

We are devoted to developing new and better preventive, diagnostic services and treatments through clinical and lab research.

LiverResearchOverview

To remain at the forefront of pediatric liver transplant research, we collaborate with other centers across the country and around the world to further our efforts and expand our understanding of pediatric liver disease. We are involved in:

  • Childhood Liver Disease Research and Education Network (ChiLDREN)—a National Institutes of Health (NIH)-sponsored collaborative network organized to study rare childhood liver diseases
  • iWith—a clinical trial for the immunosuppression withdraw for pediatric liver transplant recipients
  • Nonalcohoic Steatohepatitis (NASH) Clinical Research Network—an NIH and National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)-sponsored collaborative network that focuses on the etiology, contributing factors, history, complications and therapy of NASH
  • Pediatric Acute Liver Failure (PALF)—a multicenter, national collaborative effort to help identify, characterize and develop management strategies for children who present with acute liver failure
  • Clinical Trials in Organ Transplantation in Children (CTOT-C)—an investigative consortium sponsored by the NIH that conducts multi-institutional clinical studies that will lead to improved outcomes for pediatric transplant recipients
  • Study of Pediatric Liver Transplantation (SPLIT)—a cooperative effort among leading pediatric transplant centers in the U.S. and Canada to advance the science of pediatric liver transplants

Our areas of interest include:

  • Acute liver failure
  • Adolescent nonadherence and transition to adult care
  • Biliary atresia
  • Cystic fibrosis
  • Fatty liver disease
  • Medical issues post-transplant
  • Neonatal alloimmune liver disease
  • Neonatal cholestatic liver disease
  • Noninvasive diagnosis of liver disease using magnetic resonance imaging (MRI)
  • Nutritional outcomes of liver transplant
  • Portal hypertension
  • Transplant rejection and immunologic tolerance
ResearchHighlight
Children’s is one of only 12 sites across the U.S. enrolling patients in a national clinical research trial which, for the first time is the United States, is using an investigational liver cell infusion to treat urea cycle disorders (UCDs) in children.