Pediatric Kidney Conditions

The table listed below contains common conditions that can lead to pediatric kidney failure.

Common Kidney Conditions

Medical Name

What this means

How this hurts the kidneys

Dysplastic or cystic kidneys

Multiple cysts grow in the kidneys. They are usually present at birth.

Cysts are fluid-filled sacs that prevent the kidneys from working well.

Urinary reflux or

posterior urethral valves

Blockage in the urinary system (the kidneys, bladder and connecting tubes that make and store urine).

When urine flow is blocked, kidneys become infected and damaged.

Glomerulonephritis

A disease that can damage the part of the kidney that filters blood.

The kidneys are not able to filter out harmful substances from the blood. The body loses large amounts of protein through the urine.

Nephrotic syndrome

A disease that can damage the part of the kidneys that filters blood.

The kidneys are not able to filter out harmful substances from the blood. The body loses large amounts of protein through the urine.

Nephropathy

Kidney damage caused by continued high blood sugar levels from diabetes.

High blood sugar damages the
filtering system of the kidneys. The body loses large amounts of protein through the urine.

Lupus erythematosis or

Goodpasture’s syndrome

These are autoimmune diseases. The immune system is the body’s defense against harmful substances such as bacteria or viruses. Autoimmune diseases occur when the immune system destroys normal body tissues.

Autoimmune diseases cause inflammation of the filtering system and lining in the kidneys.

Hemolytic uremic syndrome (HUS)

Condition that affects the blood and blood vessels.

This causes kidney failure due to damage to very small blood vessels in the kidneys.

Alport syndrome

An inherited disease (passed from parent to child) that affects the glomeruli, tiny blood vessels in the kidneys that filter waste from the blood.

Kidneys are not able to filter out harmful substances from the blood. The body loses large amounts of protein through the urine.

Wegener’s syndrome

A rare disorder that causes inflammation of blood vessels in the kidneys and lungs. It may be an autoimmune disease.

Kidneys are not able to filter out harmful substances from the blood. The body loses large amounts of protein through the urine.

More Information