Research

The orthopaedic surgeons at Children’s Healthcare of Atlanta are researching and developing new techniques and therapies to better care for our young patients.

Completed Publications

Subscapularis avulsion of the lesser tuberosity in adolescent
PI: Michael Busch M.D.
This study is a long-term clinical follow-up study of patients with isolated lesser tuberosity avulsions in skeletally immature patients. Operative treatment consisted of a diagnostic arthroscopy to evaluate for concomitant pathology, followed by an open reattachment of the tuberosity through an incision in line with the anterior axillary fold.
Garrigues GE, Warnick DE, Busch MT. Subscapularis avulsion of the lesser tuberosity in adolescent. J Pediatr Orthop. 2013;33(1):8-13.  [PMID 23232372]

Effects of bracing in adolescents with idiopathic scoliosis (BrAIST)
PI: Michael Schmitz, M.D., National Institutes of Health
The BrAIST study is a Phase III, multicenter, prospective partially-randomized, partially blinded clinical trial, designed to determine whether the use of the thoracolumbosacral orthoses (brace) lowers the risk of curve progression in patients with adolescent idiopathic scoliosis (AIS) relative to observation (watchful waiting).
Weinstein SL, Dolan LA, Wright JG, Dobbs MB. Effects of bracing in adolescents with idiopathic scoliosis. N Engl J Med. 2013;369(16):1512-1521. [PMID: 23232372]

Completed Presentations

Adolescent ACL reconstruction: Autograft versus allograft.
PI: Michael Busch, M.D.
Co-Investigators: Herzog MM, May KH, Mansour W, Riboh JC, Leake MJ, Fernandez M, Willimon SC.
Presented at: American Academy of Orthopaedic Surgeons 2014 Annual Meeting. New Orleans, LA, March 11-15, 2014.

Core decompression and bone marrow aspirate concentrate for femoral head AVN secondary to sickle cell disease.
PI: Tim Schrader, M.D.
Co-Investigator: Bovid K
Poster Presented at: Pediatric Orthopaedic Society of North America 2014 Annual Meeting. Hollywood, CA, April 30-May 3, 2014.

Core decompression and bone marrow aspirate concentrate for treatment of Perthes disease.
PI: Tim Schrader, M.D.
Co-Investigator: Bovid K
Presented at: Pediatric Orthopaedic Society of North America 2014 Annual Meeting. Hollywood, CA, April 30-May 3, 2014.

Improving the process of care for developmental dysplasia of the hip.
PI: Tim Schrader, M.D.
Co-Investigator: Herzog M
Presented at: Pediatric Orthopaedic Society of North America 2014 Annual Meeting. Hollywood, CA, April 30-May 3, 2014.

Intraoperative monitoring of epiphyseal perfusion in slipped capital femoral epiphysis
PI: Tim Schrader, M.D.
Co-Investigators: Jones, CR, Kaufman, A
Presented at: The Pediatric Orthopaedic Society of North America 2013 Annual Meeting. Toronto, Ontario, Canada, May 1-4, 2013., Southern Orthopaedic Association 2013 Annual Meeting. Palm Beach, FL, July 17-20, 2013, and Eastern Orthopaedic Association 2013 Annual Meeting. Miami Beach, FL, October 30-November 2, 2013

Adolescent multidirectional shoulder instability: Arthroscopic treatment outcomes.
PI: S. Clifton Willimon, M.D.
Co-Investigators: Busch MT, Herzog MM, Warnick DE
Presented at: Pediatric Orthopaedic Society of North America 2014 Annual Meeting. Hollywood, CA, April 30-May 3, 2014.

Micheli ACL reconstruction in prepubescent youths: A retrospective outcomes study.
PI: S. Clifton Willimon, M.D.
Co-Investigators: Jones CR, May K, Herzog MM, Leake M, Busch MT.
Presented at: American Orthopaedic Society for Sports Medicine 2013 Annual Meeting. Chicago, IL, July 11-14, 2013. and Southern Orthopaedic Association 2013 Annual Meeting. Palm Beach, FL, July 17-20, 2013.

Shoulder and wrist angles in a standing back handspring in preadolescent and adolescent female gymnasts
PI: S. Clifton Willimon, M.D.
Co-Investigators: McLaren K, Byrd E, Herzog MM, Polikandriotis J  
Poster Presented at: 2014 Combined Sections Meeting of the American Physical Therapy Association. Las Vegas, NV, February 3-6, 2014.

Extramural Funded Studies

AIS treated by posterior instrumentation using the PASS LP System. Evaluation of the 3-D correction, aesthetic outcomes and quality of life
PI: Dennis Devito, M.D., Medicrea Corp.

A prospective multicenter, double-arm clinical study that will measure tridimensional correction in patients with AIS and aesthetic outcomes based on questionnaires.

Dynamic contributions to femoroacetabular impingement in adolescent athletes: a biomechanical and clinical study
PI: S. Clifton Willimon, M.D., Piedmont Society Grant
This study brings together the clinical expertise in adolescent sports medicine of Children’s Orthopaedics of Atlanta and the biomechanical expertise of the motion analysis laboratory at Georgia State University to study the role of dynamic factors in pediatric FAI.  The goal is to improve our understanding of  FAI in pediatric and adolescent athletes, and provide evidence-based treatment recommendations based on these findings.    

Toward Personalized Treatment for Osteochondritis Dissecans Based on Genomic and Micro-CT Imaging
PI: S. Clifton Willimon, M.D., Georgia Institute of Technology Seed Grant
This is a collaborative study with Department of Biomedical Engineering and the School of Biology at Georgia Institute of Technology. The purpose of this study is to quantify the molecular differences in the synovial membrane and cartilage in knee joints affected in children with Osteochondritis dissecans (OCD).  

Intramural Funded Studies

Use of Ribosomal RNA-based Polymerase Chain Reaction to Diagnose Musculoskeletal Infections in Children
PI: Jill Flanagan, M.D.
This is a study designed to use a new laboratory testing method, polymerase chain reaction (PCR) with use of ribosomal ribonucleic acid (rRNA) primers, to determine if it can improve the diagnostic accuracy of septic arthritis in children.

Intraoperative Monitoring of Epiphyseal Perfusion in Slipped Capital Femoral Epiphysis
PI: Tim Schrader, M.D.
This study evaluates an innovative method of intra-operatively monitoring femoral head (epiphyseal) perfusion in patients with slipped capital femoral epiphysis and compares those results with the subsequent development of avascular necrosis. 

Dynamic contributions to femoroacetabular impingement in adolescent athletes: a biomechanical and clinical study
PI: S. Clifton Willimon, M.D.
This study brings together the clinical expertise in adolescent sports medicine of Children’s Orthopaedics of Atlanta and the biomechanical expertise of the motion analysis laboratory at Georgia State University to study the role of dynamic factors in pediatric FAI.  The goal is to improve our understanding of FAI in pediatric and adolescent athletes, and provide evidence-based treatment recommendations based on these findings.